SWHR was founded to bring national attention to the problem of the exclusion of women from medical research and clinical trials and the need for greater federal funding for diseases and conditions prevalent in, and unique to women.Historically women had been left out of medical research studies because doctors and scientists did not believe there were important differences in how diseases affected men and women. These differences are now recognized as key factors in understanding how our bodies work and fight disease.

To help women find clinical trials in which they might like to participate, SWHR has begun to list trials that are recruiting women for various conditions. SWHR does not endorse or recommend any trial and is only providing the information as a service. Choosing to take part in a medical research study is a decision that you make with the help of family, friends, health care professionals, and others you trust and respect. Below you will find lists of clinical trials that need participants, the condition the trial is studying, who qualifies, and contact information for the research coordinators and investigators. Additional information about these trials and other clinical trials can be found at www.clinicaltrials.gov

Although we know more today and often take health advances for granted, much remains to be learned. Whether you have a disease or condition that needs treatment or are in perfect health, you can play an important role in improving health care. By volunteering to take part in a research study, you can make a valuable contribution to medical knowledge for your own health and the health of all future generations of women.

Need more information? Visit our Clinical Trials FAQ page.

The Studies

ADNI GO is a landmark research study sponsored by the National Institute on Aging (NIA) at the National Institutes of Health (NIH). It is examining the sequence and timing of events at the initial onset of mild cognitive symptoms and may help scientists to better identify who is at risk for AD, as well as the effectiveness of potential prevention and treatment strategies.This two-year, $24 million study focuses for the first time on people experiencing the very earliest complaints of memory problems that affect their daily activities. ADNI GO expands on the groundbreaking Alzheimer’s Disease Neuroimaging Initiative (ADNI), the largest and most comprehensive study of its kind to date, and will continue efforts to identify biomarkers that can help build a greater understanding of the progression of AD.

Who Qualifies

Please contact the research site in your area to see if you qualify. For a list of sites please visit the ADNI GO Study’s website.

The Research Coordinators

Please visit the ADNI GO Study’s website for a list of participating Clinical Study Research sites and their contact information.

The Studies

The XPAND Study. Evaluation of a needle free, patient controlled tissue expander. The goal of the XPAND study is to compare the AeroForm patient controlled tissue expander to traditional saline expanders used in breast reconstruction surgery.Measurements will include time to expansion and permanent implant exchange, pain and ease of use.

Who Qualifies

Participants must be women 18-65 years old, requiring tissue expansion for breast reconstruction. Written consent will be required as will compliance with the study requirements. Participants cannot be smokers, have had prior surgery or radiation at the intended expansion site, are pregnant or have currently implanted electronic devices.

The Research Coordinators

Please visit clinicaltrials.gov (NCT01425268) for a list of participating sites and the corresponding study coordinator’s contact information.

Other

www.BreastCancerTrials.org (BCT.org) is a free, nonprofit, clinical trial matching service that can help youquickly and easily find breast cancer trials that might be right foryou. BCT.org has easy-to-read trial summaries and a secure message service for contacting participating research sites. You also can signup for their trial alert service to learn about newly added trials that match your health history.

The Studies

Effects of study medication for weight loss in men and women. Testing an FDA approved drug for the purpose of weight loss in obese individuals. Dietary counseling is included for all participants.

Who Qualifies

Obese women and men who are committed to losing weight.

The Research Coordinators

Carol Mack at cmack@jamesasimonmd.com or 202-293-1000

The Studies

CABANA Catheter Ablation Versus Antiarrhythmic Drug Therapy for A trial Fibrillation. This is a comparative randomized clinical trial for the treatment of A trial Fibrillation. The intent of the CABANA trial is to enroll patients who have new onset or under-treated paroxysmal, persistent, or longstanding persistent atrial fibrillation and who warrant therapy for their arrhythmia.

Who Qualifies

Key Inclusion criteria

  1. >18 years of age.
  2. ECG-documented AF episodes >1 hour in duration.
  3. Eligible for catheter ablation and >2 sequential rhythm control and/or >3 rate control drugs.
  4. >65 yrs of age, or <65 yrs with at least one stroke riskfactor: Hypertension, diabetes mellitus, prior stroke or TIA, congestive heart failure or LVEF <35%, or left atrial enlargement (> 5.0cm).

Key Exclusion Criteria

  1. Lone AF in patients <65 years of age
  2. Patients who have failed >2 anti-arrhythmic drugs at a therapeutic dose due to inefficacy or side effects
  3. More than one week of amiodarone treatment in the past 3 months
  4. An efficacy failure of full dose amiodarone treatment >12 weeks duration at any time
  5. Reversible causes of AF including thyroid disorders, acute alcohol intoxication, recent major surgical procedures, or trauma
  6. Prior LA catheter ablation with the intention of treating AF
  7. Contraindication to warfarin anti-coagulation

The Arrhythmia Service at Johns Hopkins Medicine is currently recruiting for this trial under the direction of Dr. Hugh Calkins and Dr. Joseph Marine.

The Research Coordinators

If your physician has determined that you have an abnormal heart rhythm called atrial fibrillation that requires treatment, please contact the Johns Hopkins Research Coordinator at erobin26@jhmi.edu for study information.Visit the trial websiteThe study is registered on the clinical trials website .

The Studies

A Placebo-Controlled Trial of Lyrica for Irritable Bowel Syndrome (IBS). This study involves one study visit, taking study drug or placebo for 12 weeks, and completion of a questionnaire at home every week for 12 weeks.

Who Qualifies

Women and men over the age of 18-70 who have been diagnosed with irritable bowel syndrome (IBS).

The Research Coordinators

Annie Almazar at almazarelder.ann@mayo.edu507-284-5010

The Studies

Interstitial Cystitis and Bladder Pain Syndrome: An IC/BPS research study is currently being conducted for women between the ages of 18 and 75. The study is designed to see how well an investigational study medicine works at reducing moderate-to-severe IC/BPS pain.

Who Qualifies

Women between the ages of 18 and 75 who have IC/BPS. Clinical evidence of IC.  Have provided written informed consent

The Research Coordinators

www.BladderPainStudy.com or 866-303-5080

The Studies

Oral Treatment for Endometriosis and Associated Pain: Purpose of study is to evaluate the safety and effectiveness of a new oral medication for the management of moderate to severe endometriosis-associated pain.

Who Qualifies

Participants must be premenopausal women between 18-49 years of age and have been surgically diagnosed with endometriosis within the past seven years.

The Research Coordinators

Carol Mack at cmack@jamesasimonmd.com 202-293-1000

The Studies

Constipation from Prescription Opioid Pain Medicines:
If you regularly take a prescription opioid pain medicine, such as morphine, and also experience constipation, you may be eligible to participate in a clinical research stud. AstraZeneca is sponsoring a clinical research study to determine whether an investigational drug is safe and effective to treat constipation as a side effect in people taking opioid pain medicines. The study may last up to 18 weeks with an option to continue in the long-term safety study.

Who Qualifies

Participants must be:

  • 18 or older and live in the United States;
  • Taking at least one prescription opioid pain medicine, every day for at least four weeks; and

Also experiencing constipation

The Research Coordinators

www.theKODIACstudy.com  or call 1-866-320-6957

The Studies

  • The SECURE Study is a clinical research study of a new birth control patch
  • It will help evaluate the effectiveness and safety of an investigational transdermal contraceptive patch, called Twirla®
    • ‘Investigational’ means that the patch has not yet been approved by the FDA
    • ‘Transdermal’ means the hormones from the patch are absorbed through your skin
    • The study patch is a birth control method being studied for women who want to prevent pregnancy
    • The study patch is designed to be flexible, and is applied to the skin. It moves with you throughout all of your normal activities.
  • The study patch contains the same type of hormones that are in many combined hormonal contraceptive pills. Their use in this study is investigational.

Around 2100 women will take part in the SECURE Study across up to 70 different sites in the USA.

Who Qualifies

If you are 18 years of age or older, and willing to try a new investigational birth control patch that is being studied, then you may like to join the SECURE Study**Other study requirements (which will be assessed by the study personnel) will also need to be met before you can join the study.

The Research Coordinators

Learn more here.

The Studies

The study is performed to assess the efficacy and safety of different doses of BAY1002670 in subjects with uterine fibroids. The does-response relationship will be evaluated. Further, the study aims to establish a population pharmacokinetic/pharmacodynamics relationship for BAY 1002670 in subjects with uterine fibroids. To assess the efficacy of BAY1002670 the interchangeability of menstrual pictogram and alkaline hematin method for the judgement of menstrual blood loss will the assessed. Read more.

Who Qualifies

Women, age 18 to 50 with at least 1 uterine fibroid who have heavy menstrual periods are potential candidates for the research study.

The Research Coordinators

Click here to learn more about the study.