Scleroderma is an autoimmune disease that affects the tiny blood vessels in the fingers and other areas of the body, causing them to narrow and restrict blood flow. This frequently happens in the small blood vessels of the hands, making them extremely sensitive to cold, a problem called Raynaud’s phenomenon. Scleroderma can be localized orsystemic. About 80% of those affected by scleroderma are women.

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