Strategies and Methods to Study Sex Differences in Cardiovascular Structure and Function: A Guide for Basic Scientists

Peer-Reviewed Articles

Published 12/12/11

Members of SWHR’s Cardiovascular Disease Network authored this Biology of Sex Differences review on the importance of accounting for sex in the design and interpretation of cardiovascular disease studies.

The article describes concepts, methods, and procedures to assist in the design of animal and tissue/cell-based studies of sex differences in cardiovascular structure, function, and models of disease.

The authors write that consideration of sex, including in pharmacological effects of drugs, is essential to increase the foundation of basic knowledge upon which to build translational approaches to prevent, diagnose and treat cardiovascular diseases in humans.