Sleep, Pregnancy, And Your Future Health



By Judette Louis MD, MPH University of South Florida, SWHR Interdisciplinary Network on Sleep Member and Mary Ashley Cain MD, University of South Florida

For many women, pregnancy can be a period of anxiety and concerns. After months of watching her diet and following the doctor’s orders, a new mother now must focus on her wonderful, rapidly growing and sometimes demanding, infant. As life moves on, mothers are happy to forget all the concerns of pregnancy, unaware that pregnancy provides a window into their future health.

One particular problem, poor sleep during pregnancy, is often blamed on heartburn, frequent urination, or even the baby’s movement. Poor sleep in pregnancy, however, may be due to the worsening of a condition known as sleep apnea. Women with sleep apnea experience pauses in breathing while they sleep which results in low oxygen levels in their blood. The brain registers these pauses and wakes the woman up to resume normal breathing. Symptoms of this condition can include snoring and excessive sleepiness during the day. Recent studies have confirmed that women with sleep apnea are two times as likely to develop pregnancy complications, such as gestational diabetes, gestational hypertension, or preeclampsia [1]. Having any of these conditions makes a woman’s pregnancy riskier, and the risk continues after pregnancy ends.

Studies increasingly suggest that women who have gestational diabetes, gestational hypertension, or preeclampsia are more likely to have heart disease later in life [2]. The studies have been so consistent that the American Heart Association now recognizes gestational diabetes, gestational hypertension, and preeclampsia as risk factors for heart disease in women [3]. Considering that heart disease is the number one cause of death in women, we need to pay attention to these studies.

One important question to ask is, “how soon do we see the difference?” The answer is concerning. One study found a 20 percent increase in heart disease and stroke among women who suffer from preeclampsia as early as three to five years after delivery [4]. This finding indicates that we may need to act quickly if we want to prevent heart disease.

The next important question is, “what can we do about it?” Doctors and researchers are looking for ways to prevent heart disease in women who experience these pregnancy complications. In the meantime, there are some well-recognized ways to lower your risk of heart disease. Women who breastfeed are 20 to 30 percent less likely to develop heart disease than women who have never breastfed. In addition, the American Heart Association also recommends “Life’s Simple 7” as key factors to achieving ideal heart health [5]. They include 2 ½ hours of moderate physical activity each week, controlling cholesterol, stopping smoking, eating healthier foods, maintaining a normal body weight, controlling blood pressure, and controlling blood sugar. Outside of pregnancy, treatment of sleep apnea has also been associated with a decrease in heart disease-related deaths in women [6]. If you have sleep apnea or have had pregnancy complications, talk to your healthcare provider about what you can do to decrease your chance of developing heart disease.

The Society for Women’s Health Research Interdisciplinary Network on Sleep is committed to promoting awareness of sex and gender differences in sleep and circadian rhythms across the lifespan, and the impact they have on health and wellbeing. Learn more about the Sleep Network here.

References

1. Facco FL, Parker CB, Reddy UM, et al. Association Between Sleep-Disordered Breathing and Hypertensive Disorders of Pregnancy and Gestational Diabetes Mellitus. Obstetrics & Gynecology. 2017;129(1):31-41.

2. Rich-Edwards JW, Fraser A, Lawlor DA, Catov JM. Pregnancy characteristics and women’s future cardiovascular health: an underused opportunity to improve women’s health? Epidemiologic reviews. 2014;36(1):57-70.

3. Mosca L, Benjamin E, Berra K, et al. Effectiveness-based guidelines for the prevention of cardiovascular disease in women—2011 update: a guideline from the American Heart Association. Circulation. 2011;123(11):1-20.

4. Cain MA, Salemi JL, Tanner JP, Kirby RS, Salihu HM, Louis JM. Pregnancy as a window to future health: maternal placental syndromes and short-term cardiovascular outcomes. American journal of obstetrics and gynecology. 2016;215(4):484 e481-484 e414.

5. Sacco RL. The new American Heart Association 2020 goal: achieving ideal cardiovascular health. Journal of Cardiovascular Medicine. 2011;12(4):255-257.

6. Campos-Rodriguez F, Martinez-Garcia MA, de la Cruz-Moron I, Almeida-Gonzalez C, Catalan-Serra P, Montserrat JM. Cardiovascular mortality in women with obstructive sleep apnea with or without continuous positive airway pressure treatment cohort study. Annals of internal medicine. 2012;156(2):115-122.

By Judette Louis MD, MPH University of South Florida, SWHR Interdisciplinary Network on Sleep Member and Mary Ashley Cain MD, University of South Florida

For many women, pregnancy can be a period of anxiety and concerns. After months of watching her diet and following the doctor’s orders, a new mother now must focus on her wonderful, rapidly growing and sometimes demanding, infant. As life moves on, mothers are happy to forget all the concerns of pregnancy, unaware that pregnancy provides a window into their future health.

One particular problem, poor sleep during pregnancy, is often blamed on heartburn, frequent urination, or even the baby’s movement. Poor sleep in pregnancy, however, may be due to the worsening of a condition known as sleep apnea. Women with sleep apnea experience pauses in breathing while they sleep which results in low oxygen levels in their blood. The brain registers these pauses and wakes the woman up to resume normal breathing. Symptoms of this condition can include snoring and excessive sleepiness during the day. Recent studies have confirmed that women with sleep apnea are two times as likely to develop pregnancy complications, such as gestational diabetes, gestational hypertension, or preeclampsia [1]. Having any of these conditions makes a woman’s pregnancy riskier, and the risk continues after pregnancy ends.

Studies increasingly suggest that women who have gestational diabetes, gestational hypertension, or preeclampsia are more likely to have heart disease later in life [2]. The studies have been so consistent that the American Heart Association now recognizes gestational diabetes, gestational hypertension, and preeclampsia as risk factors for heart disease in women [3]. Considering that heart disease is the number one cause of death in women, we need to pay attention to these studies.

One important question to ask is, “how soon do we see the difference?” The answer is concerning. One study found a 20 percent increase in heart disease and stroke among women who suffer from preeclampsia as early as three to five years after delivery [4]. This finding indicates that we may need to act quickly if we want to prevent heart disease.

The next important question is, “what can we do about it?” Doctors and researchers are looking for ways to prevent heart disease in women who experience these pregnancy complications. In the meantime, there are some well-recognized ways to lower your risk of heart disease. Women who breastfeed are 20 to 30 percent less likely to develop heart disease than women who have never breastfed. In addition, the American Heart Association also recommends “Life’s Simple 7” as key factors to achieving ideal heart health [5]. They include 2 ½ hours of moderate physical activity each week, controlling cholesterol, stopping smoking, eating healthier foods, maintaining a normal body weight, controlling blood pressure, and controlling blood sugar. Outside of pregnancy, treatment of sleep apnea has also been associated with a decrease in heart disease-related deaths in women [6]. If you have sleep apnea or have had pregnancy complications, talk to your healthcare provider about what you can do to decrease your chance of developing heart disease.

The Society for Women’s Health Research Interdisciplinary Network on Sleep is committed to promoting awareness of sex and gender differences in sleep and circadian rhythms across the lifespan, and the impact they have on health and wellbeing. Learn more about the Sleep Network here.

References

1. Facco FL, Parker CB, Reddy UM, et al. Association Between Sleep-Disordered Breathing and Hypertensive Disorders of Pregnancy and Gestational Diabetes Mellitus. Obstetrics & Gynecology. 2017;129(1):31-41.

2. Rich-Edwards JW, Fraser A, Lawlor DA, Catov JM. Pregnancy characteristics and women’s future cardiovascular health: an underused opportunity to improve women’s health? Epidemiologic reviews. 2014;36(1):57-70.

3. Mosca L, Benjamin E, Berra K, et al. Effectiveness-based guidelines for the prevention of cardiovascular disease in women—2011 update: a guideline from the American Heart Association. Circulation. 2011;123(11):1-20.

4. Cain MA, Salemi JL, Tanner JP, Kirby RS, Salihu HM, Louis JM. Pregnancy as a window to future health: maternal placental syndromes and short-term cardiovascular outcomes. American journal of obstetrics and gynecology. 2016;215(4):484 e481-484 e414.

5. Sacco RL. The new American Heart Association 2020 goal: achieving ideal cardiovascular health. Journal of Cardiovascular Medicine. 2011;12(4):255-257.

6. Campos-Rodriguez F, Martinez-Garcia MA, de la Cruz-Moron I, Almeida-Gonzalez C, Catalan-Serra P, Montserrat JM. Cardiovascular mortality in women with obstructive sleep apnea with or without continuous positive airway pressure treatment cohort study. Annals of internal medicine. 2012;156(2):115-122.