Autoimmune diseases cause a person’s immune system to attack the body’s own tissues and organs, including the skin. In the U.S., an estimated 6.8 million people have been diagnosed with alopecia, 18 million with atopic dermatitis, and 8 million with psoriasis. SWHR convened a diverse and interdisciplinary working group of basic and clinical researchers, health care providers, patients/patient advocates, and policy leaders for a closed, two-day roundtable meeting to discuss the health, social, and economic impacts of alopecia, atopic dermatitis, and psoriatic arthritis on women.
Alopecia areata is an autoimmune skin disease that results in hair loss on the scalp, face, and other areas of the body. Often appearing in childhood, alopecia occurs in people of all ages, sexes, and ethnic groups, with a lifetime risk of 2.1% incidence. Alopecia is slightly more common in women than men, and there is a significant social stigma associated with female hair loss that can also lead to depression, low self-esteem, and poor patient outcomes.
Atopic dermatitis is the most common type of eczema and can come and go for years throughout an individual’s life. Atopic dermatitis affects a similar number of girls and boys; however, studies have shown it is more common in adult women than men. Because common triggers include stress and hormonal changes, atopic dermatitis affects women differently than men over the lifespan. It can also present complications during conception and pregnancy.
Psoriatic arthritis is a condition involving joint inflammation (arthritis) that most often occurs with psoriasis, a chronic inflammatory skin disease that is characterized by patches of discolored and irritated skin often covered by flaky scales. An estimated 10-30% of people with psoriasis also develop psoriatic arthritis. Women and men are affected equally with psoriatic arthritis, but studies have indicated that women have worse patient-reported outcomes for pain, swollen joint count, responses to treatment, and remission.
